Antipyretic Therapy in Patients with Sepsis
نویسندگان
چکیده
منابع مشابه
Antipyretic therapy in patients with sepsis.
Sepsis is a clinical syndrome characterized by a systemic inflammatory response to infection. Mortality rates in sepsis have remained high, despite recent advances in our understanding of the immunological mechanisms that cause sepsis. Fever, a nonspecific acute-phase response, has been associated with improved survival and shortened disease duration in some infections. This article reviews the...
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BACKGROUND AND OBJECTIVE The effect of antipyretic therapy on mortality in patients with sepsis remains undetermined. The present study aimed to investigate the role of antipyretic therapy in ICU patients with sepsis by using a large clinical database. METHODS The multiparameter intelligent monitoring in intensive care II (MIMIC- II) database was employed for the study. Adult patients with se...
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Purpose. The study aimed to investigate the effectiveness of antipyretic therapy on mortality in critically ill patients with sepsis requiring mechanical ventilation. Methods. In this study, we employed the multiparameter intelligent monitoring in intensive care II (MIMIC-II) database (version 2.6). All patients meeting the criteria for sepsis and also receiving mechanical ventilation treatment...
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BACKGROUND AND OBJECTIVE antipyretic therapy for patients with sepsis has long been debated. The present study aimed to explore the beneficial effect of antipyretic therapy for ICU patients with sepsis. DESIGN systematic review and trial sequential analysis of randomized controlled trials. DATABASE Pubmed, Scopus, EBSCO and EMBASE were searched from inception to August 5, 2014. METHODS Mo...
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Fever is among the most common manifestations of disease and antipyresis is one of the most usual therapeutic intervention undertaken. A variety of microbial products including endotoxins and exotoxins are recognized as exogenous pyrogens which induce host cells to produce mediators known as endogenous pyrogens. The best studied endogenous pyrogen is interleukin 1, others include tumor necrosis...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2000
ISSN: 1537-6591,1058-4838
DOI: 10.1086/317514